Genome-mapping

October 6, 2017

The genetic programming encoded inside us that has till today remained the most enigmatic conundrums to replicate

 

What is the origin of humanity; the tiny specs that make up our genetic code. Truth be told, the very essence of our existence holds the secret to further discoveries; our genes are the gateway to a new era of development in health. When we talk about genome we are talking about the genes and genetic materials present in a cell or in an organism. Now, with the advancements in technology scientists have been able to reach the extents of genome mapping. This allows them to move around the genes and discover people’s background, their culture, from where they belong and their ancestors. It is a work in progress.  

 

Studies of the structure and function of chromosomal features and sequence elements have much to contribute to and gain from genome mapping. Abnormalities in chromosome banding associated with specific diseases have pinpointed regions of the genome for intensive analysis. An improved understanding of chromosome organization can facilitate gene identification and isolation, as well as enabling sophisticated genetic and vector systems for genome studies to be devised. 

 

Now there are two types of genome mapping. The first one is genetic-linkage maps and the other is physical maps. These maps contain different information and each has its own strength and weakness. Genetic-linkage maps were made by tracking down multiple distinguishing characteristics such as hair colour or eye colour. The closer the genes are on a chromosome the less likely they are to be separated by crossing over. Crossing over produces chromosomes with new combinations of genes.  

 

The physical maps always gives us the physical distances from one landmark to another. STS's (sequence tagged site) which is found in one place of the genome, helps us to identify the genome. No matter how we cut it will always tell us where the pieces belong.  

 

"What is the meaning of life?" We stumble upon this question many times but our purpose is to advance in science to secure a better future. Genome map helps scientists find and learn about other parts of the genome. Maps helps scientists to track of which colleagues are studying nearby or related parts of genome. Also, genome helps scientists to compare the genome of different species. 

 

In the future, scientists hope that more detailed genome maps will help them find genes faster, leading them straight to each gene the way you can look at a road map and determine the sequence of streets that will take you exactly where you want to go. Thalassemia is the bane of hereditary diseases and genome mapping holds the key to eradicate it.

 

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